Spyre Therapeutics, Inc.
FAIR PRICE VALUATION
Updated daily
Model: DCF 50% · Relative 30% · Consensus 20%
MARKET PRICE
$74.62
FAIR PRICE
$35.94
MARGIN
$38.68
P/E Ratio
N/A
Div. Yield
N/A
ROE
-29.4%
Average
Market Cap
$4B
Mid-cap
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FPI RATING
Low debt levels and consistent growth trajectory, but volatile earnings pattern and weak profitability margins.
Analytical data, not an investment recommendation. Updated daily.
How we calculate this ↗MARGIN OF SAFETY
A 20% margin of safety below fair value — the conservative entry level for risk-aware investors.
SAFETY MARGIN
20%
Below fair value
ENTRY LEVEL
$28.75
Fair price × 0.80
DISTANCE
61.5%
Price to entry level
At the current price of $74.62, SYRE trades 61.5% above the conservative entry level of $28.75. This entry level represents a 20% margin of safety below the calculated fair price of $35.94 — a buffer that accounts for estimation uncertainty in the valuation model.
Margin of safety is a risk management concept, not an investment recommendation. The 20% threshold follows Benjamin Graham's value investing framework. Fair price and entry levels are model-based estimates updated daily. Learn more about Margin of Safety ↗
VALUATION HISTORY
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P/E RATIO HISTORY
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METHODOLOGY
How we calculate SYRE's fair price
Spyre Therapeutics, Inc.'s fair price of $35.94 is derived from a blended model that combines DCF analysis (50%), relative valuation against Healthcare peers using metrics like P/E and EV/EBITDA (30%), and analyst consensus (20%). At the current market price of $74.62, SYRE trades 51.8% above its calculated fair value.
DCF MODEL · 50%
Discounted free cash flow analysis based on projected cash flows, discounted at a rate reflecting SYRE's risk profile.
RELATIVE · 30%
Comparing SYRE's valuation multiples against Healthcare peers to determine if the stock is over or undervalued relative to its industry.
ANALYST · 20%
Aggregated analyst price targets for SYRE, weighted by recency and analyst accuracy.
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Want to test your own assumptions? Use our free calculators to estimate SYRE's fair value with your own inputs.
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What is the fair price of SYRE?+
Based on our blended model combining DCF analysis (50%), relative valuation against Healthcare peers (30%), and analyst consensus (20%), the fair price for Spyre Therapeutics, Inc. is $35.94. At the current market price of $74.62, SYRE trades 51.8% above its calculated fair value.
Is SYRE overvalued or undervalued?+
Spyre Therapeutics, Inc. is currently overvalued based on our valuation model. The stock trades at $74.62, which is 51.8% above the fair price of $35.94.
What is the margin of safety for SYRE?+
With a 20% margin of safety applied to the fair price of $35.94, the conservative entry level for SYRE is $28.75. At the current market price of $74.62, the stock trades 61.5% above this entry level. Margin of safety is a risk management concept from Benjamin Graham's value investing framework, not an investment recommendation.
How often is SYRE's fair price updated?+
We update fair price calculations for SYRE daily after market close. The current fair price of $35.94 incorporates the latest market data and sector multiples.
What factors affect SYRE's fair price calculation?+
SYRE's fair price of $35.94 is derived from DCF analysis (50% weight), relative valuation against Healthcare peers (30% weight), and analyst consensus (20% weight)., ROE of -29.4%.
Is SYRE a good buy right now?+
At $74.62, SYRE trades 51.8% above our fair value estimate of $35.94. The stock is currently overvalued. ROE stands at -29.4% (average). Fair Price Index provides valuation data — always do your own research before investing.
Does SYRE pay dividends?+
SYRE does not currently pay a dividend.
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Fair Price Index is for informational purposes only and does not constitute investment advice. Fair value calculations are model-based estimates and may not reflect actual market conditions. Always conduct your own research before making investment decisions.